Beyond p-value: The Rigor and Power of Study

Fengyu Zhang, Claude Hughes

Received June 29, 2019, Accepted December 6, 2019


There have been a series of recent discussions and debates on the p-value and statistical significance, which has been taught in statistics and used in research for nearly a century after R.A. Fisher. These discussions, including publications of more than 40 papers in a special issue of the American Statistician, provide an excellent opportunity to think about some technical measures for practical implementation in grant applications and publications. While several factors have been discussed, it may be the rigor of a study that determines the p-value for reporting study results and judging a consistent replication of research. Based on the Fisherian and Neyman-Pearson theory for statistical hypothesis testing, we propose new criteria, which can be implemented without fundamental changes in existing statistics, to reduce false positives and irreplicability of studies that are either inadequately powered or overpowered.


P-value, rigor of study, statistical power, statistical hypothesis testing, statistical significance

Copyright © 2019 by Global Clinical and Translational Research.

How to cite this article:

Zhang, F and Hughes CL. Beyond p-value: the rigor and power of study. Glob Clin Transl Res. 2020; 2(1):1-6. DOI:10.36316/gcatr.02.0021. DOI:10.36316/gcatr.02.0021.

Comments in

HC Kraemer. A comment on “Beyond p-value: the rigor and power of study”. Glob Clin Transl Res. 2020; 2(1):7-9. doi:10.36316/gcatr.02.0022. 

S Wu. Improve reproducibility by using appropriate statistical methods. Glob Clin Transl Res. 2020; 2(1):10-11. doi:10.36316/gcatr.02.0023. 

A Hendrix. A comment on “Beyond p-value: the rigor and power of study”. Glob Clin Transl Res. 2020; 2(1):12. doi:10.36316/gcatr.02.0024. 

F Zhang, C Hughes. Authors’ reply to comments. Glob Clin Transl Res. 2020; 2(1):12. doi:10.36316/gcatr.02.0025.


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