Open Access

Novel Attention Training in Children with Attention Deficit/Hyperactivity Disorder

Yanting Hou, Si Dai, Yidong Shen, Jianjun Ou

February 16, 2030



Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder marked by an ongoing inattention and/or hyperactivity-impulsivity pattern. Traditional treatments targeting attentional aspects are associated with drug side effects, costly expenses, and poor compliance. This review aims to present novel approaches to attention training, such as using digital interventions to improve cognitive function mediated by video games, eye trackers, and gesture recognition sensors. The merit and shortages of these novel approaches and some new ideas of attention training in ADHD are discussed.


ADHD; attention training; video games; eye-tracking

Copyright© 2023 by the author(s). Licensee Global Clinical and Translational Research Institute, Inc., Bethesda, MD. This is an open-access article distributed under the terms and conditions of the Creative Commons Attribution License (CCBY4.0,, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.

How to cite this article. Hou Y, Dai S, Shen Y, Ou J. Novel attention training in children with attention deficit/hyperactivity disorder. Glob Clin Transl Res. 2023; 5(1): 12-15. DOI:10.36316/gcatr.05.0048


1.         Polanczyk GV, Willcutt EG, Salum GA, Kieling C, Rohde LA. ADHD prevalence estimates across three decades: an updated systematic review and meta-regression analysis. Int J Epidemiol. 2014;43(2):434-42.

2.         Caye A, Swanson JM, Coghill D, Rohde LA. Treatment strategies for ADHD: an evidence-based guide to select optimal treatment. Mol Psychiatry. 2019;24(3):390-408.

3.         Sonuga-Barke EJ, Brandeis D, Cortese S, Daley D, Ferrin M, Holtmann M, et al. Nonpharmacological interventions for ADHD: systematic review and meta-analyses of randomized controlled trials of dietary and psychological treatments. Am J Psychiatry. 2013;170(3):275-89.

4.         Cortese S, Coghill D. Twenty years of research on attention-deficit/hyperactivity disorder (ADHD): looking back, looking forward. Evid Based Ment Health. 2018;21(4):173-6.

5.         Patra S, Nebhinani N, Viswanathan A, Kirubakaran R. Atomo-xetine for attention deficit hyperactivity disorder in children and adolescents with autism: A systematic review and meta-analysis. Autism Res. 2019;12(4):542-52.

6.         Catalá-López F, Hutton B, Núñez-Beltrán A, Mayhew AD, Page MJ, Ridao M, et al. The pharmacological and non-pharmacological treatment of attention deficit hyperactivity disorder in children and adolescents: protocol for a systematic review and network meta-analysis of randomized controlled trials. Syst Rev. 2015;4:19.

7.         Castells X, Blanco-Silvente L, Cunill R. Amphetamines for attention deficit hyperactivity disorder (ADHD) in adults. Cochrane Database Syst Rev. 2018;8(8):Cd007813.

8.         Catalá-López F, Hutton B, Núñez-Beltrán A, Page MJ, Ridao M, Macías Saint-Gerons D, et al. The pharmacological and non-pharmacological treatment of attention deficit hyperactivity disorder in children and adolescents: A systematic review with network meta-analyses of randomised trials. PLoS One. 2017;12(7):e0180355.

9.         Salmi J, Salmela V, Salo E, Mikkola K, Leppämäki S, Tani P, et al. Out of focus - Brain attention control deficits in adult ADHD. Brain Res. 2018;1692:12-22.

10.      Kollins SH, DeLoss DJ, Cañadas E, Lutz J, Findling RL, Keefe RSE, et al. A novel digital intervention for actively reducing severity of paediatric ADHD (STARS-ADHD): a randomised controlled trial. Lancet Digit Health. 2020;2(4):e168-e78.

11.      Peñuelas-Calvo I, Jiang-Lin LK, Girela-Serrano B, Delgado-Gomez D, Navarro-Jimenez R, Baca-Garcia E, et al. Video games for the assessment and treatment of attention-deficit/hyperactivity disorder: a systematic review. Eur Child Adolesc Psychiatry. 2022; 31(1):5-20.

12.      Bikic A, Leckman JF, Lindschou J, Christensen T, Dalsgaard S. Cognitive computer training in children with attention deficit hyperactivity disorder (ADHD) versus no inter-vention: study protocol for a randomized controlled trial. Trials. 2015;16:480.

13.      Pandian GSB, Jain A, Raza Q, Sahu KK. Digital health interventions (DHI) for the treatment of attention deficit hyperactivity disorder (ADHD) in children - a comparative review of literature among various treatment and DHI. Psychiatry Res. 2021;297:113742.

14.      Garcia-Zapirain B, de la Torre Díez I, López-Coronado M. Dual System for Enhancing Cognitive Abilities of Children with ADHD Using Leap Motion and eye-Tracking Technologies. J Med Syst. 2017;41(7):111.

15.      García-Baos A, D'Amelio T, Oliveira I, Collins P, Echevarria C, Zapata LP, et al. Novel Interactive Eye-Tracking Game for Training Attention in Children With Attention-Deficit/ Hyperactivity Disorder. Prim Care Companion CNS Disord. 2019;21(4):19m02428.

16.      Bikic A, Leckman JF, Christensen T, Bilenberg N, Dalsgaard S. Attention and executive functions computer training for attention-deficit/hyperactivity disorder (ADHD): results from a randomized, controlled trial. Eur Child Adolesc Psychiatry. 2018;27(12):1563-74.

17.      Cortese S, Kelly C, Chabernaud C, Proal E, Di Martino A, Milham MP, et al. Toward systems neuroscience of ADHD: A meta-analysis of 55 fMRI studies. The American Journal of Psychiatry. 2012;169:1038-55.

18.      Shams TA, Foussias G, Zawadzki JA, Marshe VS, Siddiqui I, Müller DJ, et al. The Effects of Video Games on Cognition and Brain Structure: Potential Implications for Neuropsychiatric Disorders. Curr Psychiatry Rep. 2015;17(9):71.

19.      Hoffman LG. Incidence of vision difficulties in children with learning disabilities. J Am Optom Assoc. 1980;51(5):447-51.

20.      Karatekin C, Asarnow RF. Exploratory eye movements to pictures in childhood-onset schizophrenia and attention-deficit/hyperactivity disorder (ADHD). J Abnorm Child Psychol. 1999;27(1):35-49.

21.      Munoz DP, Armstrong IT, Hampton KA, Moore KD. Altered control of visual fixation and saccadic eye movements in attention-deficit hyperactivity disorder. J Neurophysiol. 2003;90(1):503-14.

22.      Zee DS, Leigh RJ, Mathieu-Millaire F. Cerebellar control of ocular gaze stability. Ann Neurol. 1980;7(1):37-40.

23.      Rayner K. Eye movements and attention in reading, scene perception, and visual search. Q J Exp Psychol (Hove). 2009;62(8):1457-506.

24.      Cubillo A, Halari R, Smith A, Taylor E, Rubia K. A review of fronto-striatal and fronto-cortical brain abnormalities in children and adults with Attention Deficit Hyperactivity Disorder (ADHD) and new evidence for dysfunction in adults with ADHD during motivation and attention. Cortex. 2012;48(2):194-215.

25.      Asiry O, Shen, H., & Calder, P. . Extending attention span of ADHD children through an eye tracker directed adaptive user interface. Proceedings of the ASWEC 2015 24th Australasian Software Engineering Conference 2015, 149-152.

26.      Janmohammadi S, Haghgoo HA, Farahbod M, Overton PG, Pishyareh E. Effect of a visual tracking intervention on attention and behavior of children with Attention Deficit Hyperactivity Disorder. J Eye Mov Res. 2020;12(8):10.

27.      Bashiri A, Ghazisaeedi M, Shahmoradi L. The opportunities of virtual reality in the rehabilitation of children with attention deficit hyperactivity disorder: a literature review. Korean J Pediatr. 2017;60(11):337-43.

28.      Fang Y, Han D, Luo H. A virtual reality application for assessment for attention deficit hyperactivity disorder in school-aged children. Neuropsychiatr Dis Treat. 2019;15: 1517-23.

29.      Hong N, Kim JJ, Kwon JH, Eom H, Kim E. Effect of Distractors on Sustained Attention and Hyperactivity in Youth With Attention Deficit Hyperactivity Disorder Using a Mobile Virtual Reality School Program. J Atten Disord. 2021: 1087054720986229.

30.      Jahn FS, Skovbye M, Obenhausen K, Jespersen AE, Miskowiak KW. Cognitive training with fully immersive virtual reality in patients with neurological and psychiatric disorders: A systematic review of randomized controlled trials. Psychiatry Res. 2021;300:113928.